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Looking at comparable GLP-1 medications can give us a ballpark idea: Wegovy (semaglutide) pens have a list price of about $1,350 per month without insurance

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Similarly, the Semaglutide Effects on Cardiovascular Outcomes in People with Overweight or Obesity (SELECT) trial demonstrated a significant reduction in cardiovascular events in individuals with overweight or obesity, with subsequent analysis addressing prespecified kidney endpoints

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Following either local secretion or systemic circulation to target tissues, IGF-1 primarily exerts its biological effects through binding to the IGF-1 receptor (IGF-1R), with minimal interaction occurring through the insulin receptor (IR) (Figure 2) (Werner, 2023)

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