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Seek prompt or urgent referral to a dermatologist if there are red-flag features, including: suspected scarring alopecia (indicated by pain, erythema, scaling, or pustules on the scalp)

At the conclusion of the experiment, peripheral blood and tissues from the lungs, heart, liver, spleen, and kidneys were harvested

It helps heal wounds, reduce inflammation, and fight against free radicals

Therapeutic strategies targeting this cycle -such as Nrf2 activators (sulforaphane), mitochondrial antioxidants (MitoQ), and AGE inhibitors (aminoguanidine)- highlight the dual role of OS as interventions early in DM, which can improve -cell function, while later-stage treatments primarily mitigate complications

Considering that energy metabolism is also able to regulate ROS levels, we supplemented sodium pyruvate (the sodium salt form of pyruvate, a key energy substrate for cellular metabolism) or JX06 (a compound that modulates pyruvate flux into the tricarboxylic acid cycle) in GGCT-knockdown cells, respectively