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While metformin has long served as the standard first-line therapy, many clinicians are now reconsidering whether a metformin-first and wait strategy is enough for this higher-risk population

At the same time, it slows down how quickly your stomach empties and sends signals to your brain that make you feel full

PMID: 24373234

Understanding the maintenance landscape is part of designing the best overall protocol

One meta-analysis of several studies published in 2021 showed that metabolicbariatric surgery in patients with obesity extended their life-survival by nine years (Syn, Cummings, Wang