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Renal Effects of SGLT2 Inhibitors: an Update

doi: 10.1016/j.micpath.2017.02.031 156 GuiHLiuXWangZWHeDYSuDFDaiSM

HepG2 cells exhibited higher catalase activity than HeLa cells, and inhibiting catalase activity by using 3-aminotriazole (3-AT, a specific inhibition of catalase) or catalase siRNA remarkably reduced the resistance of HepG2 cells to ROS, demonstrating the key roles of catalase for the strong resistance of HepG2 cells to ROS

Targeting SRC coactivators blocks the tumor-initiating capacity of cancer stem-like cells

IGF-I, which mediates most of the effects of GH on skeletal metabolism, promotes chondrogenesis and increases bone formation by regulating the functions of the differentiated osteoblasts[357, 358]