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Key limitations hindering clinical translation include: (1) Formula standardization gaps : Current research predominantly focuses on empirical or self-formulated TCM prescriptions, with insufficient validation of classical prescriptions through randomized controlled trials

In contrast, VaD is characterized by the presence of vascular lesions such as white matter hyperintensities, lacunar infarcts, or large cortical infarcts, which can be seen in MRI or CT scans 66

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T.et al (2016)