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SIN itself has been reported to cross the bloodbrain barrier and reach brain tissue after systemic administration

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To date, only few studies have examined the effects of LC supplementation for at least 12 weeks, which is, on the other hand, the main limitation of the current review

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Four clinical stages (or phases) are defined for untreated patients with a history of acetaminophen poisoning who subsequently develop acetaminophen-induced hepatotoxicity and liver failure (Table 2)