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The research identified a 9% relative increase in depression risk and 2.2% absolute risk difference in GLP-1 RA users one year following treatment initiation

A 45-year-old woman with refractory ulcerative colitis achieved clinical remission after eight weeks of oral BPC-157 , confirmed by endoscopy

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Mechanistically, the binding of BPC157 to FBXO22 induces steric hindrance that suppresses FBXO22-mediated ubiquitination and degradation of its substrate BACH1