Why Chronic Inflammation Matters Chronic inflammation is now recognized as a central driver of nearly every chronic disease we fear most, including: Cardiovascular disease Diabetes and metabolic syndrome Autoimmune conditions Alzheimers and other neurodegenerative diseases Its also a major contributor to biological aging
Kezelman, S., Touyz, S., Hunt, C
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This stress is shown by the overexpression of iNOS, an enzyme primarily involved in the mitochondrial lipid peroxidation, with consequent damage of the cell membrane, which is validated by the accumulation of intracellular MDA: a hallmark of lipoperoxidation
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