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The porcupine plot revealed an interesting pattern of dynamics between the head and leg regions of the v3 integrin, in which the ligand-binding site containing the -propeller and I domains made inward motion toward the calf-2 domain of the leg region, possibly transmitting the activation signal directly to the leg region attached to the transmembrane tail

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A heritable form of megaesophagus has been suggested for cats, particularly for Siamese cats, although no detailed studies have been performed.13, 29 It is often frustrating to determine the underlying cause of acquired megaesophagus