Y.KimJ.-J.KimB.-E.et al (2018)
Type 2 Diabetes Segment Accounts for the Largest Share of the GLP-1 Market In terms of the target indication, the market is segmented into Alzheimers Disease, non-alcoholic steatohepatitis, obesity, sleep apnea, and type 2 diabetes
[DOI] [PMC free article] [PubMed] [Google Scholar] 211.Marano G., Rossi S., Sfratta G., Traversi G., Lisci F.M., Anesini M.B., Pola R., Gasbarrini A., Gaetani E., Mazza M
GLP-1 receptor agonists have now received FDA approvals for cardiovascular risk reduction, obstructive sleep apnea, and chronic kidney disease, in addition to their original diabetes and obesity indications
ECL1 forms two hydrogen bonds with Q23 P (via W214 ECL1 ) and E27 P (via Q211 ECL1 ), as well as stacking interaction with F28 P (via W214 ECL1 )