A: Yes, especially if they contain allergens or degraded compounds
Altern Ther Health Med 20:4854 Rashid J, Kumar SS, Job KM, Liu X, Fike CD, Sherwin CMT (2020) Therapeutic potential of citrulline as an arginine supplement: a clinical pharmacology review
Operator: "Hello 111, what's your problem today?" Me: "I think I might have taken a paracetamol overdose." Operator: "How many tablets have you taken in the last 24 hours?" Me: "I only really remember taking two, but I was drunk, and I've just got this feeling that I've taken an overdose." Operator: "But you can only remember taking two tablets
10.1016/j.foodchem.2013.02.104 12 AnnaC.-A.LdiaC.VctorP.MayteB.MontserratP.Mara-JosM.et al (2012)
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