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Serious but less common adverse effects include pancreatitis, gallbladder disease, acute kidney injury (particularly in the setting of dehydration from gastrointestinal symptoms), and hypoglycemia when used in combination with insulin or sulfonylureas

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"One of the things that I realized the very first time I took a GLP-1 was that all these years I thought that thin peoplethose peoplehad more willpower," Winfrey told Jastreboff, adding that she believed, "They ate better foods