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As with any medication, individual results can vary

J Biol Chem 270: 26488-26496, 1995

A systematic review and meta-analysis of studies involving semaglutide treatment for NAFLD/nonalcoholic steatohepatitis (NASH) found significant improvements in liver enzymes, liver stiffness, and metabolic parameters, suggesting its potential as a therapeutic option for this prevalent condition

Liraglutide attenuates the osteoblastic differentiation of MC3T3E1 cells by modulating AMPK/mTOR signaling

The thought is that the GLP-1 agonists mechanism of action can lead to pancreatic cell hyperplasia (since the GLP-1 receptors are in the islet beta cells and exocrine duct cells), leading to a back up in pressureand you got it, inflammation