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Diabetes Care, 36(8), 1542-1558

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Adults with Type 2 Diabetes or obesity-related conditions who have completed the standard two-month titration schedule (0.25mg to 0.5mg) and are ready for full maintenance therapy under ongoing medical supervision

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Research has also described a distinct potency pattern across its receptor targets: Strong GIP receptor activity (around 8.9 higher than native GIP) Moderate GLP-1 receptor activation (about 0.4 relative potency) Modest glucagon receptor activity (about 0.3 relative potency) This balanced profile provides a framework for studying coordinated metabolic responses rather than isolated single-pathway effects

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