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Each format offers different tradeoffs

While these may be more expensive, patient assistance programs offered by manufacturers like Novo Nordisk and Eli Lilly can help alleviate some of the financial burden

Gastrointestinal Issues GI side effects are the most common, especially early on: Nausea Vomiting Diarrhea Constipation These may lessen over time but can persist in some patients, leading to dehydration and nutritional deficiencies

In the VITACOG trial, high-dose B vitamins in older adults with mild cognitive impairment and elevated homocysteine reduced atrophy in the gray matter regions most vulnerable to Alzheimers disease, with the placebo group losing about 3.7 percent and the treatment group about 0.5 percent over two years