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The unintended consequence

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More importantly, a 24-hr 50 M APR-246 treatment had no effect on recognition of mutant p53 by pAB-1620 (Fig

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Furthermore, the involvement of CHAC1 in non-malignant diseases, such as diabetes, liver injury, and respiratory disorders, adds complexity, as its therapeutic modulation could potentially worsen these conditions by disrupting GSHmetabolism and increasing oxidative stress