Moreover, the gut microbiota and its associated metabolites promote the differentiation and function of anti-inflammatory macrophages, Treg cells, CD4 + CD8 + regulatory cells, IL-10 + and/or IL-35 + B regulatory cells, as well as IL-22-producing innate lymphoid cells 3 (ILC3), which are involved in maintaining the gut mucosal homeostasis (Su et al., 2022) and protecting the kidneys (Su et al., 2022)
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The medication also influences dopamine and serotonin pathways in the central nervous system, neurotransmitters directly tied to energy, mood, and motivation
While vitamin B12 injections are commonly recommended for individuals with a diagnosed deficiency or those at risk of deficiency due to certain medical conditions or dietary restrictions, they can also benefit: Vegetarians and Vegans : Plant-based diets may lack sufficient sources of vitamin B12, making injections a valuable option for keeping optimal levels
Based on the current Phase I results, CT-996 will advance into Phase II clinical development
