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NICE Technology Appraisal TA1026: Tirzepatide for managing overweight and obesity

GLP-1s for Chronic Kidney Disease GLP-1s for Advanced Liver Disease In August 2025, the FDA approved Wegovy (semaglutide) to treat adults with a type of liver disease called metabolic-associated steatohepatitis (MASH) with moderate to advanced liver scarring (fibrosis), when used alongside diet and exercise

This improved sense of control can be particularly encouraging for individuals who previously felt overwhelmed by hunger or emotional triggers

These typically emerge in the first two to four weeks and improve as the body adapts

Who's accountable when the agent gets it wrong