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Neuron 97 , 368377 (2018)
Among these, non-covalent DPP1 inhibitors have attracted considerable attention due to their unique pharmacokinetic characteristics and potential safety advantages ( 10 Comparison of DPP1 inhibitors with other treatment strategies 10.1 Comparison with direct NSP inhibitors Direct NSP inhibitors, particularly NE inhibitors such as AZD9668, have undergone Phase II studies in bronchiectasis patients but failed to significantly improve patient clinical symptoms ( Superiority of upstream regulation represents a key advantage
149 It results in cell dysfunction, 150 leading to the initiation of a vicious cycle that further aggravates metabolic diseases and NAFPD
Many patients benefit from a combination approach, particularly when addressing both hormonal and metabolic goals simultaneously
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