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In aged oocytes, abnormal CG congregation near the chromosomes was observed, indicating disruption in cytoplasmic organization

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The unsupervised clustering of 4453 fibroblasts was used to analyze the senescent cells in keloid and normal skin fibroblast based on senescence-associated marker genes, CDKN2A, TP53, CDKN1A (also known as p21 ) , LMNB1, H2AFX, TP53BP1, SFRP4, CCND1 and GLB1 according as previously reference 20,21

Suzuki, N., Uebaba, K., Kohama, T., Moniwa, N., Kanayama, N., & Koike, K