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Human studies One clinical study investigated the effect of pro- and prebiotic supplementation on ES-induced behavior in the offspring
SIRT1 targets NF-B directly, and by deacetylating it, it can modulate the amount of acetylation of NF-B, which in turn controls the transcription level of iNOS and other inflammatory factors 106
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Group V (PPA-GABA), the GABA-therapeutic group, received the same oral PPA dose as Group II, then orally given GABA supplementation
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