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The theory of excessive opioid peptides The theory of opioid system overload by exogenous foodderived peptides in individuals with ASD or schizophrenia postulates that deficiency of the enzyme DPPIV and/or other proteases that cleave the amino acid proline bond leads to excessive production of opioid peptides derived from gluten and casein in the intestinal lumen

The consistent thread across these communities is that people treat BPC-157 vs TB-500 as a both, for different reasons conversation rather than a winner-take-all comparison a lay echo of the same local-versus-systemic distinction the preclinical literature describes

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