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Firstly, the 1-g and 4-g PV1 sVLP doses tested in the study contain 187 and 748 DU, respectively, which are much higher than a single human dose (40 DU) of commercial IPV, making it difficult to directly compare the immunogenicity of sVLP and IPV

Lastly, in order to avoid exclusion of values that are disorder/group specific and can provide insight into the nature of a disorder, a straight cut-off score (which is usually used) is not recommended 80

It is a mixture of fragmented molecules derived from the breakdown of the bacteria lactococcus lactis

It means the clinical evidence is building and that patients pursuing this path need a clinician who can assess their individual response, not just apply a template

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