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In the FIGHT [80] and LIVE [81] RCTs performed in patients with HF and reduced ejection fraction with and without T2DM, liraglutide treatment, compared to placebo, did not demonstrate a beneficial effect on left ventricular function, with a trend towards harm [80, 81]

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In the United Kingdom, the regulatory body responsible for such substances is the Medicines and Healthcare products Regulatory Agency (MHRA)

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