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The short answer is that while there is no documented major drug-herb interaction in clinical literature specifically for this pair, the combination is considered high-risk for certain individuals

hence, more studies are needed to be done to clearly identify this interaction

In a Phase 1 randomized, double-blind clinical study targeting obese participants (NCT04478708), AMG133 demonstrated acceptable safety, tolerability, and significant dose-dependent weight loss

Fridays says its providers might order initial blood tests, and it has an arrangement with Quest Diagnostics that provides a discount to patients who need to get blood work

Normal adjustment includes mild nausea, decreased appetite, slight stomach discomfort, and fatigue that gradually improve over days to weeks