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Although oral Semaglutide offers a non-injectable dosing option, it faces a number of challenges, notably bioavailability, metabolic stability, and gastrointestinal side effects (Ke et al., 2024) (Table 2)

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its largest market by far until 2032, patent expirations in India, Canada, Brazil, and China this year are likely to have a sizable impact on its revenue

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More importantly for researchers considering stacking scenarios, the compound increased lean body mass without altering subcutaneous fat distribution