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Patients should be counseled that weight loss plateaus are normal and do not indicate medication failure

P., Schiff, J

Regarding safety, the overall incidence of AEs was similar between the dose and placebo groups

This dual role suggests that p53 may act as a promising therapeutic target in OA therapy, achieving the synergistic effect of eliminating lesioned cells while protecting normal tissues by precisely regulating the balance between apoptosis and ferroptosis in different cell populations

Seek urgent medical attention if you develop sudden or severe neurological symptoms, such as significant weakness, loss of coordination, visual disturbances, or confusion, as these may indicate more serious neurological complications requiring immediate assessment