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The assay was performed as biological replicates of GLP-1MK-801 (Cys-linked) ( n = 3), GLP-1MK-801 (hCys-linked) ( n = 2), GLP-1MK-801 (Pen-linked) ( n = 3)

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In its briefing materials, FDA staff concluded the evidence weighed against adding these peptides, citing limited proof of effectiveness, gaps in how the substances are chemically characterized, and unresolved questions about impurities and immune reactions

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Semaglutide causes delayed gastric emptying