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Headache Mild stomach upset Flatulence Nausea and vomiting Patients with bipolar disorder may develop mania Patient Warnings: Patients taking selective serotonin reuptake inhibitors (SSRIs), monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, or other drugs that affect serotonin levels should avoid taking SAM-e without the supervision of a physician due to case reports of mania and serotonin syndrome, a serious condition, or other side effects

Patient Registration & Medical History: Collection of patient details, skin concerns, and a review of medical history, including any history of insulin resistance, hormonal issues (like PCOS), or medications that may contribute to pigmentation changes

Funding This study was supported by the National Institute of Health (NIH) under grant NIH 5 R44 MH107124-03 and generous investment by the Nancy Lurie Marks Family Foundation and the Robert E

Shoba, G., Joy, D., Majeed, M., et.a

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