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Tissue distribution and biological functions beyond glucose metabolism: 2.2.1
If side effects are intolerable at a particular dose level, clinicians may recommend maintaining that dose for an additional 4 weeks before escalating, or reducing to the previous dose temporarily
Similar content being viewed by others Introduction Alcohol use disorder (AUD) remains a major public health challenge, affecting over 10% of the U.S
Medications like semaglutide (Ozempic, Wegovy), a glucagon-like peptide 1 (GLP-1) agonist, and tirzepatide (Mounjaro, Zepbound), a GLP-1 and gastric inhibitory peptide (GIP) receptor agonist, have taken the weight loss world by storm because of their dramatic results
Specifically, GLP-1 has been shown to stimulate the electrical activity of the hypothalamic proopiomelanocortin neurons in the ARC by enhancing protein kinase A production and by increasing L-type calcium channel expression [38]
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