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All analyses were performed using linear mixed models with family-factor as random effect, in order to take into account the pedigree structure of the sample

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Therefore, this data set is unique, to our knowledge, and allowed a comprehensive analysis of rhythmic genes, protein expression, and associated metabolic pathways, as well as the effect of the deletion of the circadian clock regulator BMAL1 on these processes (of note, BMAL1 is a transcription factor that may have functions unrelated to the circadian clock)

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