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Eur J Pharmacol 459(23):255262
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doi: 10.1097/MIB.0000000000000955 65 Gomez-BrisRSaezAHerrero-FernandezBRiusCSanchez-MartinezHGonzalez-GranadoJM
PKA phosphorylates the transcription factor MITF (microphthalmia-associated transcription factor), upregulating tyrosinase and melanogenic enzymes
Second, head-to-head comparative trials between GLP-1 RA monotherapy, dual agonists, and triple agonists in MASH populations with histological endpoints are entirely lacking: current selection among agents relies on indirect comparisons across trials with different inclusion criteria and follow-up periods
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