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So, the data which the authors provide on this topic in their report is pretty much worthless, and they are silent on the topic which would have been most relevant: How much longer, or shorter, did pimobendan dogs live than did placebo dogs before dying MVD-related deaths

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Furthermore, some of the potential targets (including Bcl-2 family proteins involved in apoptosis) of these stress-activated protein kinases need to be experimentally demonstrated in the future