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three levels of GSH or Zn

Unlike earlier GLP-1 receptor agonists like semaglutide (Ozempic/Wegovy) that target a single hormone pathway, or tirzepatide (Mounjaro/Zepbound) that targets two, retatrutide activates three distinct metabolic receptors : GIP, GLP-1, and glucagon

Although acknowledged in the guidelines of the American Thoracic Society and the European Respiratory Society, more robust studies need to be conducted to further elucidate its applicability [58]

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4.2.2 Methodological limitations 4.2.2.1 Study design challenges A PCB occupational exposure study involving 89 workers exemplifies common methodological limitations that can obscure true exposure-response relationships