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High and low molecular weight hyaluronic acid differentially influences oxylipins synthesis in course of neuroinflammation

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The research primarily focuses on cognitive performance, Alzheimers disease, Parkinsons disease, dementia, and neurodegenerative markers such as amyloid plaques and neurofibrillary tangles

Additionally, the combined effects of oxidative stress and excitotoxicity activate both caspase-dependent and caspase-independent apoptotic pathways, leading to cellular fragmentation and neurodegeneration

The next step in kidney handling of UA is an energy-dependent process of tubular secretion of roughly 50% of filtered UA load