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(2022) 14:e23009

S2CID 15573624

289 The rise in cAMP activates PKA, a versatile protein kinase that phosphorylates various target proteins

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As a result, most dermatologists now consider microdermabrasion to be an outdated technique for skin lightening, preferring more advanced and targeted treatments such as chemical peels, laser therapy, or topical skincare products with proven skin lightening ingredients