Mahadevan KK, Mcandrews KM, Lebleu VS, Yang S, Lyu H, Li B, et al
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She explains that the first two studies, conducted by Darryn Willoughby's team, used different forms of citrulline (L-citrulline vs
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363 Reduced activity and expression of the GLUT-1 transporter in the BBB suggest decreased glucose uptake and utilization by the brain, 360,363 which may further exacerbate cerebrovascular degeneration, BBB breakdown, and A pathology in models overexpressing APP, inducing neurodegeneration and cognitive deficits (Fig