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[11] Any future GLP-1 patch would require robust clinical trial evidence demonstrating efficacy, safety, and pharmacokinetic profiles comparable to existing injectable formulations before regulatory approval could be granted

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At lower content of selenium, the ratio of GSH to GSSG did not increase significantly, probably due to the adaptive increase in GSH, which was an attempt to maintain the normal level of GSH to GSSG in the yeast cellular cytosol