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The exact mechanisms through which activation of THR improves MASH are still unclear but are known to control fat synthesis, regulate fatty acid oxidation, regulate cholesterol metabolism, improve mitochondrial function, and reduce inflammation and fibrosis
2 2.8.3 Widely targeted metabolomics analysis Frozen tissue specimens were homogenized and extracted using ice-cold methanol:water (7:3, v/v) supplemented with isotope-labeled internal standards,followed by multi-platform LC-MS/MS analysis
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Glucagon-like peptide-1 (GLP-1) belongs to the incretin family, renowned for its glucose-dependent insulinotropic and appetite-suppressing functions [1]
Patients should consult a qualified healthcare professional and verify current FDA and pharmacy requirements before making treatment decisions.
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