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The following information was derived from each of the trials, including the publication details (clinical trial number and trial phase, source of funding, author, year of publication, country), participant profiles (age and BMI at baseline, percentage of female, ethnicity, comorbidity), treatment characteristics (sample size, placebo controlled, trial duration, dosage, with or without lifestyle intervention), and outcome measures

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In this view, the NHLBI recommended that the development of improved RBC storage practices be guided by omics phenotyping 8,29,30 as we performed in the present study