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How it detoxifies: Glutathione binds to metals, making them water-soluble for excretion via urine or bile

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Table 1) Sleep abnormalities Individuals with PWS have sleep-disordered breathing, including central and obstructive sleep apnea, abnormal arousal, abnormal circadian rhythm in REM sleep, reduced REM latency, and abnormal response to hypercapnia 26, 27 as well as excessive daytime sleepiness

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