The formulation demonstrated significant anti-psoriatic effects, including reduced epidermal hyperplasia, erythema , and inflammatory infiltration , as well as favorable in vitro permeation and skin deposition profiles
AOD9604 is strictly for laboratory research use only and is not approved for medical, cosmetic, or dietary applications.
Figure 4: Glutathione conjugation with 1,2-dibromoethane causing formation of the highly reactive episulphonium ion [Figure source: Timbrell (2009) Biochemical Mechanisms of Toxicity.4 th Ed
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J Biol Chem 274: 1221312216 BienM,LongenS,WagenerN,ChwallaI,HerrmannJM,RiemerJ (2010) Mitochondrial disulfide bond formation is driven by intersubunit electron transfer in Erv1 and proofread by glutathione