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The simulated profiles for the reduced and comproportionation models, as well as the parameter values generated from the fitting process, are located in the supplementary information

Research on the relationship between dosage and efficacy has not been well-established, thus further clinical studies are required to identify optimal dosage regimes for certain health effects with consideration of an individuals age, individual condition and health status

Loh et al., 2024)

Hanks balanced salt solution containing calcium and magnesium ions, and mixed well to make 200 nM Mito-Tracker Red CMXRos working solution

Formulators also blend gentler esters like retinyl acetate or retinyl palmitate with small retinol amounts to mimic the results of 0.02% tretinoin while minimizing dermatitis