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The testes (or testicles) are the male gonads, the site of sperm production and maturation

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As permeant ion channel blockers of AMPARs and KARs, cytoplasmic polyamines (spermine, spermidine, putrescine) have been identified as critical modulators of neuronal signaling, influencing action potential firing rates as well as the efficacy of neurotransmission (Nichols and Lopatin, 1997)

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