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It is also advised to avoid mega doses of pyridoxine in pregnant or breastfeeding patients unless necessary, since safety data for doses beyond the recommended dietary allowance are limited

Cytoprotection Research has also examined protective effects in gastrointestinal tissues together with broader cellular stress responses

Chen Sci Rep 2025;15:18063

In research settings, it is examined as an isolated pentadecapeptide with consistent physicochemical characteristics, which supports its use across biochemical, cellular, and preclinical experimental platforms

Preclinical studies in rodents have demonstrated reductions in fat mass, improved insulin sensitivity, and increased metabolic rate without significant changes to food intake (Neelakantan et al., 2019)