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Furthermore, mitochondrial membrane potential (m) decline, increased mitochondrial outer membrane permeability and mitochondrial DNA (mtDNA) damage have been identified as key regulatory factors in ferroptosis (10,11)

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FIGURE 1 2.4 Subacute oral toxicity study Subacute oral toxicity study was performed based on the guidelines provided by the Organisation for Economic Co-operation and Development No.407 (OECD 407), Repeated Dose 28-day Oral Toxicity Study in Rodents (OECD, 2008)

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