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Dose titration should be gradual, and antiemetic strategies may be required

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[175] An observational study on people with obesity and type 2 diabetes and heart failure with preserved ejection fraction, semaglutide had about a 42% lower risk of hospitalization for heart failure and all-cause death combined compared with sitagliptin

We are committed to exploring solutions for #RareDisease where unmet need persists

Jennifer Ashton, ABC News chief medical correspondent and a board-certified obesity medicine specialist, said on "Good Morning America." Those with obesity may struggle to manage long-term weight loss with changes in diet and exercise alone