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El International Citicoline Trial on acUte Stroke (ICTUS) es un estudio multicntrico y doble ciego que evalu el efecto de suplementar a 2,298 pacientes con accidente cerebrovascular isqumico agudo con citicolina (2,000 mg/da) o un placebo durante seis semanas sobre varios resultados funcionales y neurolgicos y en la tasa de mortalidad (94)