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Serious but Rare Side Effects Both medications carry warnings for more serious but uncommon side effects, occurring in less than 1-2% of patients: Pancreatitis (inflammation of the pancreas) Kidney problems Severe allergic reactions Thyroid tumors (seen in animal studies) Gastroparesis (delayed stomach emptying) Serious stomach issues Vision problems in some diabetics Retatrutides side effect profile appears similar to that of other incretin-based medications, though long-term safety data remains limited due to its investigational status

Bikou A, Dermiki-Gkana F, Penteris M, Constantinides TK, Kontogiorgis C

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Really, whatever fits into your lifestyle in a way that makes it consistent for you is the best choice for that patient

Its worth noting, however, that berberine can come with side effects, such as diarrhea, constipation, and abdominal pain