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It also affects the central nervous system by increasing gamma-aminobutyric acid (GABA) levels, a neurotransmitter that reduces brain overactivity and promotes relaxation

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Researchers propose that the peptide's brief presence is sufficient to trigger a cascade of gene expression changesincluding activation of transcription factors c-Fos, c-Jun, and Egr-1that initiate self-sustaining healing processes well beyond the peptide's physical presence

When the body cant use thiamine effectively, it can create a state known as pseudohypoxia. This means that even with enough oxygen present, cells act as if theyre oxygen-starved

11 , R165 (2009)